منابع مشابه
Selenium and thyroid autoimmunity
The trace element selenium (Se) occurs in the form of the amino acid selenocysteine in selenoproteins. Selenoproteins exerts multiple physiological effects in human health, many of which are related with regulation of reduction-oxidation processes. In fact, the selenoenzyme families of glutathione peroxidase (GPx) and thioredoxin reductase (TRx) display the ability to act as antioxidants, prote...
متن کاملSelenium and thyroid.
Inadequate supply of the essential trace element selenium (Se) has been associated with predisposition for, or manifestation of, various human diseases such as Keshan and Kashin-Beck disease, cancer, impaired immune function, neurodegenerative and age-related disorders and disturbances of the thyroid hormone axis. Se deficiency in combination with inadequate iodine contributes to the pathogenes...
متن کاملSelenium-induced thyroid dysfunction.
Administration of the anti-oxidative trace element selenium is currently being evaluated for its benefits in patients with inflammatory diseases. However, little is known about the risks of selenium. We report on a patient in whom, along with standard therapy, administration of large intravenous doses of selenite for sepsis secondary to pneumonia resulted in development of marked hypothyroidism...
متن کاملSelenium, the thyroid, and the endocrine system.
Recent identification of new selenocysteine-containing proteins has revealed relationships between the two trace elements selenium (Se) and iodine and the hormone network. Several selenoproteins participate in the protection of thyrocytes from damage by H(2)O(2) produced for thyroid hormone biosynthesis. Iodothyronine deiodinases are selenoproteins contributing to systemic or local thyroid horm...
متن کاملAntioxidants and Thyroid disorders
It is well known that oxidative stress (OS), defined as an imbalance between radicals and antioxidant defense, is implicated as a pathophysiological mechanism of different diseases and is a topic of growing interest. Cell injury is a consequence of OS; recognized targets are DNA, lipids and proteins, which react with hydroxyl radicals to form specific products1. Especially in the field of cardi...
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ژورنال
عنوان ژورنال: INTERNATIONAL JOURNAL OF ENDOCRINOLOGY
سال: 2015
ISSN: 2307-1427,2224-0721
DOI: 10.22141/2224-0721.7.71.2015.72597